MEMORIA 2021 - Área 3. Enfermedades Digestivas y Endocrino-Metabólicas

Área 3. Enfermedades Digestivas y Endocrino-Metabólicas

OBJETIVOS CIENTÍFICOS VINCULADOS AL PLAN ESTRATÉGICO

Generar conocimiento científico de excelencia: el Área 3 ha publicado menos artículos que en 2020 pero de mayor calidad, consiguendo el mejor impacto medio y acumulado de la serie histórica. Ese crecimiento no ha reducido la capacidad de liderazgo de sus investigadores, liderando el 65% de los artículos. Los indicadores de citación también han mejorado notablemente.
Captación de talento científico: la concesión de 6 ayudas competitivas de recursos humanos es la mejor de la serie histórica de este área, destacando la concesión de un investigador Miguel Servet. Además, con fondos de investigación (tanto competitivos como no competitivos) el personal de apoyo a la investigación ha pasado de 25 personas a 43. El área ha crecido con la incorporación de un grupo emergente (liderado por un Miguel Servet) y por un grupo clínico asociado.
Dinamizar la captación de recursos: la captación de recursos competitiva ha sido menor en número de ayudas pero mejor en financiación, superando los 2.5 millones de euros. Destacamos la participación en la red RICORS “Primary Care Interventions to Prevent Maternal and Child Chronic Diseases or Perinatal and Developmental Origin”. La facturación por investigación clínica no ha tenido un incremento significativo.

10 Grupos de Investigación

CIRUGÍA DIGESTIVA, ENDOCRINA Y TRASPLANTE DE ÓRGANOS ABDOMINALES (CONSOLIDADO)
NUTRICIÓN (CONSOLIDADO)
BASES CLÍNICAS, TECNOLÓGICAS, CELULARES Y MOLECULARES EN MEDICINA DIGESTIVA (CLÍNICO ASOCIADO)
ODONTOLOGÍA (EMERGENTE)
ODONTOLOGÍA MÍNIMAMENTE INVASIVA (EMERGENTE)
INVESTIGACIÓN QUIRÚRGICA EN ÁREA DE SALUD (CONSOLIDADO)
NUTRICION Y BROMATOLOGIA (CONSOLIDADO)
TOXICOLOGÍA Y EVALUACIÓN DE RIESGOS (EMERGENTE)
OBESIDAD, DIABETES Y METABOLISMO (EMERGENTE)
CIRUGÍA ORTOPÉDICA INFANTIL Y RECONSTRUCTIVA ÓSEA (CLÍNICO ASOCIADO)

INDICADORES GENERALES

120

Nº Publicaciones

904.75

Impacto Total

7.54

Impacto Medio

Tipo	Nº Pubs	FI total	FI Medio
Originales	101 (84.17%)	793.9	7.86
Revisiones	19 (15.83%)	110.85	5.83

67.5

Q1%

25.83

D1%

FI >= 15

Tipo	Nº Q1	Nº D1	Nº FI >= 15
Originales	68	27	7
Revisiones	13	4	0

INDICADORES DE LIDERAZGO

78 (65.0%)

Nº Publicaciones

408.51

Impacto Total

5.24

Impacto Medio

	Nº Pubs	FI total	FI Medio
Mujer	43 (55.13%)	206.53	4.8
Hombre	35 (44.87%)	201.98	5.77

58.97

Q1%

14.1

D1%

FI >= 15

	Nº Q1	Nº D1	Nº FI >= 15
Mujer	24	5	0
Hombre	22	6	1

OTROS INDICADORES

24.01

HCP10% (2017-2021)

54.97

HCP10 Liderado% (2017-2021)

27.15

HCP10 Lid. Mujeres% (2017-2021)

2.04

Crown (2017-2021)

61.67

Open Access%

46.67

Col. International%

* Se muestran las 5 especies, los 10 genes y las 20 enfermedades más nombradas. Los valores están normalizados logarítmicamente en base al número de publicaciones.

INDICADORES EVOLUTIVOS

DESTACADAS

Colmenero J, Rodriguez-Peralvarez M, Salcedo M, ..., Pons JA*. Epidemiological pattern, incidence, and outcomes of COVID-19 in liver transplant patients. Journal of Hepatology, 2021, 74, 148-155, PMID: 32750442, FI: 30.083

Tapia-Abellan A*, Angosto-Bazarra D*, Alarcon-Vila C, ..., Pelegrin P*. Sensing low intracellular potassium by NLRP3 results in a stable open structure that promotes inflammasome activation. Science Advances, 2021, 7, eabf4468, PMID: 34524838, FI: 14.957

Robles-Campos R*, Brusadin R, Lopez-Lopez V, ..., Parrilla-Paricio P. A New Surgical Technique Variant of Partial ALPPS (Tourniquet Partial-ALPPS). Annals of Surgery, 2021, 273, e22-e24, PMID: 32740247, FI: 13.787

Fernandez JA*, Alconchel F*, Gomez B, ..., Ramirez P*. Unresectable GIST liver metastases and liver transplantation: A review and theoretical basis for a new indication. International Journal of Surgery, 2021, 94, 106126, PMID: 34592432, FI: 13.4

Garcia-Castillo J*, Alcaraz-Perez F, Martinez-Balsalobre E, ..., Cayuela ML*. Telomerase RNA recruits RNA polymerase II to target gene promoters to enhance myelopoiesis. Proceedings of the National Academy of Sciences of the United States of America, 2021, 118, PMID: 34353901, FI: 12.779

LISTADO COMPLETO

Andreeva L, David L, Rawson S, ..., Pelegrin P et al. NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation. Cell, 2021, 184, 6299-6312.e22, PMID: 34861190, FI: 66.85

COVIDSurg Collaborative COLABORADORES: Glasbey J, Ademuyiwa A, Adisa A, ..., Alconchel F et al. Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study. Lancet Oncology, 2021, 22, 1507-1517, PMID: 34624250, FI: 54.433

Glasbey JC, Nepogodiev D, Simoes JFF et al. COLABORADORES: Glasbey JC, Nepogodiev D, Simoes JF, ..., Alconchel F et al. Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study. Journal of Clinical Oncology, 2021, 39, 66-78, PMID: 33021869, FI: 50.717

Ximendes E, Marin R, Shen Y, ..., Garcia-Carrillo, N, et al. Infrared-Emitting Multimodal Nanostructures for Controlled In Vivo Magnetic Hyperthermia. Advanced Materials, 2021, 33, e2100077, PMID: 34117667, FI: 32.086

Gaul S, Leszczynska A, Alegre F, ..., Pelegrin P et al. Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis. Journal of Hepatology, 2021, 74, 156-167, PMID: 32763266, FI: 30.083

Hewitt G, Borel V, Segura-Bayona S, ..., Tomas-Loba A et al. Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD. Molecular Cell, 2021, 81, 767-783.e11, PMID: 33333017, FI: 19.328

Cherqui D, Ciria R, Kwon CHD, ..., Alconchel F et al. Expert Consensus Guidelines on Minimally Invasive Donor Hepatectomy for Living Donor Liver Transplantation From Innovation to Implementation: A Joint Initiative From the International Laparoscopic Liver Society (ILLS) and the Asian-Pacific Hepato-Pancreato-Biliary Association (A-PHPBA). Annals of Surgery, 2021, 273, 96-108, PMID: 33332874, FI: 13.787

Mueller M, Breuer E, Mizuno T, ..., Lopez-Lopez V et al. Perihilar Cholangiocarcinoma - Novel Benchmark Values for Surgical and Oncological Outcomes From 24 Expert Centers. Annals of Surgery, 2021, 274, 780-788, PMID: 34334638, FI: 13.787

COVIDSurg Collaborative COLABORADORES: Nepogodiev D, Simoes JF, Li E, ..., Harrison EM et al. Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study. Anaesthesia, 2021, 76, 1454-1464, PMID: 34371522, FI: 12.893

COVIDSurg Collaborative COLABORADORES: Nepogodiev D, Simoes JF, Li E, ..., Harrison EM et al. Timing of surgery following SARS-CoV-2 infection: an international prospective cohort study. Anaesthesia, 2021, 76, 748-758, PMID: 33690889, FI: 12.893

COVIDSurg Collaborative COLABORADORES: Dajti I, Valenzuela JI, Boccalatte LA, ..., Aguayo-Albasini JL et al. Machine learning risk prediction of mortality for patients undergoing surgery with perioperative SARS-CoV-2: the COVIDSurg mortality score. British Journal of Surgery, 2021, 108, 1274-1292, PMID: 34227657, FI: 11.122

COVIDSurg Collaborative, GlobalSurg Collaborative COLABORADORES: Nepogodiev D, Simoes JFF, Li E, ..., Abboud OS et al. SARS-CoV-2 vaccination modelling for safe surgery to save lives: data from an international prospective cohort study. British Journal of Surgery, 2021, 108, 1056-1063, PMID: 33761533, FI: 11.122

STARSurg Collaborative and COVIDSurg Collaborative COLABORADORES: McLean KA, Kamarajah SK, Chaudhry D, ..., Alconchel F et al. Death following pulmonary complications of surgery before and during the SARS-CoV-2 pandemic. British Journal of Surgery, 2021, 108, 1448-1464, PMID: 34871379, FI: 11.122

Orenes-Pinero E, Bano F, Navas-Carrillo D, ..., Ramirez P. Evidences of SARS-CoV-2 virus air transmission indoors using several untouched surfaces: A pilot study. Science of the Total Environment, 2021, 751, 142317, PMID: 33182011, FI: 10.753

Dulsat-Masvidal M, Lourenco R, Lacorte S, ..., Espin S et al. A review of constraints and solutions for collecting raptor samples and contextual data for a European Raptor Biomonitoring Facility. Science of the Total Environment, 2021, 793, 148599, PMID: 34328978, FI: 10.753

Nunez-Sanchez MA, Herisson FM, Cluzel GL et al. Metabolic syndrome and synbiotic targeting of the gut microbiome Current Opinion in Food Science, 2021, 41, PMID: null, FI: 9.8

Soriano-Teruel PM, Garcia-Lainez G, Marco-Salvador M, ..., Pelegrin P et al. Identification of an ASC oligomerization inhibitor for the treatment of inflammatory diseases. Cell Death & Disease, 2021, 12, 1155, PMID: 34903717, FI: 9.685

Pellegrini C, Fornai M, Benvenuti L, ..., Pelegrin P et al. NLRP3 at the crossroads between immune/inflammatory responses and enteric neuroplastic remodelling in a mouse model of diet-induced obesity. British Journal of Pharmacology, 2021, 178, 3924-3942, PMID: 34000757, FI: 9.473

Zorrilla-Vaca A, Stone AB, Ripolles-Melchor J et al. COLABORADORES: Garcia-Perez C, Higuera-Miguelez E, Marcos-Vidal JM, ..., Soria-Aledo V et al. Institutional factors associated with adherence to enhanced recovery protocols for colorectal surgery: Secondary analysis of a multicenter study. Journal of Clinical Anesthesia, 2021, 74, 110378, PMID: 34144497, FI: 9.375

Contributors to the C4 article. COLABORADORES: ..., Alconchel, F, ... C4 article: Implications of COVID-19 in transplantation. American Journal of Transplantation, 2021, 21, 1801-1815, PMID: 33040483, FI: 9.369

Brouwers B, Coppola I, Vints K, ..., Ramos-Molina B* et al. Loss of Furin in beta-Cells Induces an mTORC1-ATF4 Anabolic Pathway That Leads to beta-Cell Dysfunction. Diabetes, 2021, 70, 492-503, PMID: 33277337, FI: 9.337

da Silva IV, Cardoso C, Martinez-Banaclocha H, ..., Pelegrin P* et al. Aquaporin-3 is involved in NLRP3-inflammasome activation contributing to the setting of inflammatory response. Cellular and Molecular Life Sciences, 2021, 78, 3073-3085, PMID: 33231721, FI: 9.207

Gallego R SE, Penuela GA, Martinez-Lopez E*. Enzymatic activity changes in striped catfish Pseudoplatystoma magdaleniatum, induced by exposure to different concentrations of ibuprofen and triclosan. Chemosphere, 2021, 271, 129399, PMID: 33482525, FI: 8.943

Lopez-Martinez-Carrasco Antonio, Juarez Jose M., Campos Manuel* et al. A methodology based on Trace-based clustering for patient phenotyping Knowledge-Based Systems, 2021, 232, PMID: null, FI: 8.139

Martinez Zamora L, Penalver R, Ros G, Nieto G. Innovative Natural Functional Ingredients from Olive and Citrus Extracts in Spanish-Type Dry-Cured Sausage "Fuet". Antioxidants, 2021, 10, PMID: 33513815, FI: 7.675

Bonmati-Carrion MA*, Tomas-Loba A*. Melatonin and Cancer: A Polyhedral Network Where the Source Matters. Antioxidants, 2021, 10, PMID: 33535472, FI: 7.675

Cuevas S*, Pelegrin P*. Pyroptosis and Redox Balance in Kidney Diseases. Antioxidants & Redox Signaling, 2021, 35, 40-60, PMID: 33559516, FI: 7.468

Bernabe-Garcia M*, Martinez-Balsalobre E*, Garcia-Moreno D, ..., Alcaraz-Perez F*, Cayuela ML*. Telomerase reverse transcriptase activates transcription of miR500A to inhibit Hedgehog signalling and promote cell invasiveness. Molecular Oncology, 2021, 15, 1818-1834, PMID: 33713376, FI: 7.449

Martinez-Zamora L, Penalver R, Ros G, Nieto G. Substitution of synthetic nitrates and antioxidants by spices, fruits and vegetables in Clean label Spanish chorizo. Food Research International, 2021, 139, 109835, PMID: 33509460, FI: 7.425

Espin S, Andevski J, Duke G, ..., Garcia-Fernandez AJ. A schematic sampling protocol for contaminant monitoring in raptors. Ambio, 2021, 50, 95-100, PMID: 32399779, FI: 6.943

Gazquez A*, Larque E. Towards an Optimized Fetal DHA Accretion: Differences on Maternal DHA Supplementation Using Phospholipids vs. Triglycerides during Pregnancy in Different Models. Nutrients, 2021, 13, PMID: 33557158, FI: 6.706

Lopez-Jornet P*, Collado Y, Zambudio A et al. Chemosensory Function in Burning Mouth Syndrome a Comparative Cross-Sectional Study. Nutrients, 2021, 13, PMID: 33668711, FI: 6.706

Garcia-Pola M, Pons-Fuster E, Suarez-Fernandez C, ..., Lopez-Jornet P*. Role of Artificial Intelligence in the Early Diagnosis of Oral Cancer. A Scoping Review. Cancers, 2021, 13, PMID: 34572831, FI: 6.575

Cardiothoracic Interdisciplinary Research Network and COVIDSurg Collaborative COLABORADORES: Akowuah E, Benson RA, Caruana EJ, ..., Alconchel F,... Early outcomes and complications following cardiac surgery in patients testing positive for coronavirus disease 2019: An international cohort study. Journal of Thoracic and Cardiovascular Surgery, 2021, 162, e355-e372, PMID: 33933259, FI: 6.439

Fan C, Asico LD, Villar VAM, ..., Cuevas S et al. NFAT5 Is Involved in GRP-Enhanced Secretion of GLP-1 by Sodium. International Journal of Molecular Sciences, 2021, 22, PMID: 33921209, FI: 6.208

Coppola I, Brouwers B, Meulemans S, Ramos-Molina B et al. Differential Effects of Furin Deficiency on Insulin Receptor Processing and Glucose Control in Liver and Pancreatic beta Cells of Mice. International Journal of Molecular Sciences, 2021, 22, PMID: 34198511, FI: 6.208

Hliwa A, Ramos-Molina B, Laski D et al. The Role of Fatty Acids in Non-Alcoholic Fatty Liver Disease Progression: An Update. International Journal of Molecular Sciences, 2021, 22, PMID: 34199035, FI: 6.208

Sanchez-Alcoholado L, Laborda-Illanes A, Otero A, ..., Ramos-Molina B et al. Relationships of Gut Microbiota Composition, Short-Chain Fatty Acids and Polyamines with the Pathological Response to Neoadjuvant Radiochemotherapy in Colorectal Cancer Patients. International Journal of Molecular Sciences, 2021, 22, PMID: 34502456, FI: 6.208

De Miguel C, Pelegrin P, Baroja-Mazo A*, Cuevas S*. Emerging Role of the Inflammasome and Pyroptosis in Hypertension. International Journal of Molecular Sciences, 2021, 22, PMID: 33494430, FI: 6.208

Pelegrin P*. P2X7 receptor and the NLRP3 inflammasome: Partners in crime. Biochemical Pharmacology, 2021, 187, 114385, PMID: 33359010, FI: 6.1

de Torre-Minguela C, Gomez AI, Couillin I, Pelegrin P*. Gasdermins mediate cellular release of mitochondrial DNA during pyroptosis and apoptosis. Faseb Journal, 2021, 35, e21757, PMID: 34233045, FI: 5.834

Hernandez-Gonzalez T, Gonzalez-Barrio R*, Escobar C, ..., Garaulet M*. Timing of chocolate intake affects hunger, substrate oxidation, and microbiota: A randomized controlled trial. Faseb Journal, 2021, 35, e21649, PMID: 34164846, FI: 5.834

Gallego-Rios SE, Penuela GA, Martinez-Lopez E*. Updating the use of biochemical biomarkers in fish for the evaluation of alterations produced by pharmaceutical products. Environmental Toxicology and Pharmacology, 2021, 88, 103756, PMID: 34662733, FI: 5.785

Planes-Munoz D, Frontela-Saseta C*, Ros-Berruezo G, Lopez-Nicolas R*. Effect of Gazpacho, Hummus and Ajoblanco on Satiety and Appetite in Adult Humans: A Randomised Crossover Study. Foods, 2021, 10, PMID: 33809354, FI: 5.561

Febrero B, Segura P, Ruiz-Manzanera JJ, ..., Rodriguez JM. Uncommon tumors in multiple endocrine neoplasia (MEN) type 1: Do they have a relationship with the prognosis of these patients? Journal of Endocrinological Investigation, 2021, 44, 1327-1330, PMID: 32909176, FI: 5.467

Uhl O, Lewis RM, Hirschmugl B, ..., Gazquez A et al. Placental polar lipid composition is associated with placental gene expression and neonatal body composition. Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 2021, 1866, 158971, PMID: 34029703, FI: 5.228

Martinez-Alarcon L*, Liarte S*, Quereda JJ, ..., Ramis G*. Profiling Human CD55 Transgene Performance Assist in Selecting Best Suited Specimens and Tissues for Swine Organ Xenotransplantation. Biology-Basel, 2021, 10, PMID: 34439979, FI: 5.168

Castillo-Felipe C, Franco-Martinez L, Tvarijonaviciute A, Lopez-Jornet P et al. Proteomics-Based Identification of Salivary Changes in Patients with Burning Mouth Syndrome. Biology-Basel, 2021, 10, PMID: 34062870, FI: 5.168

Garcia-Sanchez R, Mardas N, Buti J, Ortiz Ruiz AJ et al. Immediate implant placement in fresh alveolar sockets with a minimal split-thickness envelope flap: A randomised controlled clinical trial. Clinical Oral Implants Research, 2021, 32, 1115-1126, PMID: 34218469, FI: 5.021

Vicente A*, Ortiz-Ruiz AJ, Gonzalez-Paz BM, ..., Bravo-Gonzalez LA. Effectiveness of a toothpaste and a serum containing calcium silicate on protecting the enamel after interproximal reduction against demineralization. Scientific Reports, 2021, 11, 834, PMID: 33437013, FI: 4.996

Gaul S, Schaeffer KM, Opitz L, ..., Pelegrin P et al. Extracellular NLRP3 inflammasome particles are internalized by human coronary artery smooth muscle cells and induce pro-atherogenic effects. Scientific Reports, 2021, 11, 15156, PMID: 34312415, FI: 4.996

Martinez-Nicolas A*, Guaita M, Santamaria J, ..., Rol MA*. Ambulatory circadian monitoring in sleep disordered breathing patients and CPAP treatment. Scientific Reports, 2021, 11, 14711, PMID: 34282278, FI: 4.996

Lopez Jornet P*, Hernandez L, Gomez Garcia F et al. A Clinical Study on the Efficacy and Tolerability of a New Topical Gel and Toothpaste in Patients with Xerostomia: A Randomized Controlled Trial. Journal of Clinical Medicine, 2021, 10, PMID: 34884343, FI: 4.964

Lopez-Jornet P*, Zamora Lavella C, Pons-Fuster Lopez E et al. Oral Health Status in Older People with Dementia: A Case-Control Study. Journal of Clinical Medicine, 2021, 10, PMID: 33514062, FI: 4.964

Angosto-Bazarra D*, Molina-Lopez C, Penin-Franch A, ..., Pelegrin P*. Techniques to Study Inflammasome Activation and Inhibition by Small Molecules. Molecules, 2021, 26, PMID: 33803783, FI: 4.927

Baenas N, Iniesta C, Gonzalez-Barrio R, ..., Garcia-Alonso FJ*. Post-Harvest Use of Ultraviolet Light (UV) and Light Emitting Diode (LED) to Enhance Bioactive Compounds in Refrigerated Tomatoes. Molecules, 2021, 26, PMID: 33805959, FI: 4.927

Castellano-Castillo D, Ramos-Molina B, Oliva-Olivera W et al. Genome Profiling of H3k4me3 Histone Modification in Human Adipose Tissue during Obesity and Insulin Resistance. Biomedicines, 2021, 9, PMID: 34680480, FI: 4.757

Kuchay MS, Martinez-Montoro JI, Choudhary NS, ..., Ramos-Molina B*. Non-Alcoholic Fatty Liver Disease in Lean and Non-Obese Individuals: Current and Future Challenges. Biomedicines, 2021, 9, PMID: 34680463, FI: 4.757

Gazquez A*, Rodriguez F, Sanchez-Campillo M, ..., Larque E*. Adiponectin agonist treatment in diabetic pregnant rats. Journal of Endocrinology, 2021, 251, 1-13, PMID: 34156347, FI: 4.669

Migueles JH, Martinez-Nicolas A, Cadenas-Sanchez C et al. Activity-rest circadian pattern and academic achievement, executive function, and intelligence in children with obesity. Scandinavian Journal of Medicine & Science in Sports, 2021, 31, 653-664, PMID: 33095931, FI: 4.645

Pardo-Zamora G, Moreno-Rodriguez JA, Ortiz-Ruiz AJ*. Non-Incised Papilla Surgical Approach and Leukocyte Platelet-Rich Fibrin in Periodontal Reconstruction of Deep Intrabony Defects: A Case Series. International Journal of Environmental Research and Public Health, 2021, 18, PMID: 33802261, FI: 4.614

Guerrero-Girones J, Alcaina-Lorente A, Ortiz-Ruiz C et al. Biocompatibility of a HA/beta-TCP/C Scaffold as a Pulp-Capping Agent for Vital Pulp Treatment: An In Vivo Study in Rat Molars. International Journal of Environmental Research and Public Health, 2021, 18, PMID: 33918101, FI: 4.614

Pardo-Zamora G, Ortiz-Ruiz AJ, Camacho-Alonso F, ..., Vicente-Hernandez A*. Short Dental Implants (</=8.5 mm) versus Standard Dental Implants (>/=10 mm): A One-Year Post-Loading Prospective Observational Study. International Journal of Environmental Research and Public Health, 2021, 18, PMID: 34073250, FI: 4.614

Hasyima Omar M, Gonzalez Barrio R, Pereira-Caro G et al. In vitro catabolism of 3',4'-dihydroxycinnamic acid by human colonic microbiota. International Journal of Food Sciences and Nutrition, 2021, 72, 511-517, PMID: 33238790, FI: 4.444

Ortiz-Ruiz AJ*, Martinez-Marco JF, Perez-Silva A et al. Influence of Fluoride Varnish Application on Enamel Adhesion of a Universal Adhesive. Journal of Adhesive Dentistry, 2021, 23, 47-56, PMID: 33512115, FI: 4.309

Aerts L, Terry NA, Sainath NN, ..., Ramos-Molina B* et al. Novel Homozygous Inactivating Mutation in the PCSK1 Gene in an Infant with Congenital Malabsorptive Diarrhea. Genes, 2021, 12, PMID: 34068683, FI: 4.141

Nunez-Gomez V, Periago MJ, Navarro-Gonzalez I, ..., Gonzalez-Barrio R. Influence of Raspberry and Its Dietary Fractions on the In vitro Activity of the Colonic Microbiota from Normal and Overweight Subjects. Plant Foods for Human Nutrition, 2021, 76, 494-500, PMID: 34697672, FI: 4.124

Camacho-Alonso F, Garcia-Carrillo N, Buendia AJ et al. Regeneration of lingual musculature in rats using myoblasts over porcine bladder acellular matrix. Oral Diseases, 2021, 27, 1580-1589, PMID: 33031620, FI: 4.068

Rios A, Lopez Navas AI, Rigabert M, ..., Ramirez P. Usefulness of an organ donation opinion survey as a tool to promote organ donation among the adolescent population. Transplant International, 2021, 34, 2138-2145, PMID: 34486763, FI: 3.842

Lopez-Lopez V, Robles-Campos R, Garcia-Calderon D, ..., Parrilla-Paricio P. Applicability of 3D-printed models in hepatobiliary surgey: results from "LIV3DPRINT" multicenter study. Hpb, 2021, 23, 675-684, PMID: 33071150, FI: 3.842

Wanis KN, Linecker M, Madenci AL, ..., Brusadin R et al. Variation in complications and mortality following ALPPS at early-adopting centers. Hpb, 2021, 23, 46-55, PMID: 32456975, FI: 3.842

Lopez-Lopez V, Garcia-Carrillo N, de Gea D, ..., Robles-Campos R. Assessment of hepatic function, perfusion and parenchyma attenuation with indocyanine green, ultrasound and computed tomography in a healthy rat model: Preliminary determination of baseline parameters in a healthy liver. Plos one, 2021, 16, e0261447, PMID: 34919595, FI: 3.752

Arguelles-Prieto R*, Madrid JA, Rol MA*, Bonmati-Carrion MA*. Correlated color temperature and light intensity: Complementary features in non-visual light field. Plos one, 2021, 16, e0254171, PMID: 34252130, FI: 3.752

El-Messery TM, Aly E, Lopez-Nicolas R, ..., Ros G. Bioaccessibility and antioxidant activity of PCL-microencapsulated olive leaves polyphenols and its application in yogurt. Journal of Food Science, 2021, 86, 4303-4315, PMID: 34496055, FI: 3.693

Lopez-Berenguer G, Perez-Garcia JM, Garcia-Fernandez AJ, Martinez-Lopez E*. High Levels of Heavy Metals detected in Feathers of an Avian Scavenger Warn of a High Pollution Risk in the Atacama Desert (Chile). Archives of Environmental Contamination and Toxicology, 2021, 81, 227-235, PMID: 34100967, FI: 3.692

Vicente A*, Bravo-Gonzalez LA*, Navarro JA et al. Effects of diabetes on oxidative stress, periodontal ligament fiber orientation, and matrix metalloproteinase 8 and 9 expressions during orthodontic tooth movement. Clinical Oral Investigations, 2021, 25, 1383-1394, PMID: 32643088, FI: 3.606

Seoane J, Warnakulasuriya S, Bagan JV, ..., Lopez-Jornet P et al. Assembling a consensus on actinic cheilitis: A Delphi study. Journal of Oral Pathology & Medicine, 2021, 50, 962-970, PMID: 33998055, FI: 3.539

de Groot N, Farinas F, Faba L, ..., Ramis G*. Fermented rye with Agaricus subrufescens and mannan-rich hydrolysate based feed additive to modulate post-weaning piglet immune response. Porcine Health Management, 2021, 7, 60, PMID: 34886904, FI: 3.535

Lopez-Lopez V*, Ruiz-Manzanera JJ, Eshmuminov D, ..., Ramirez-Romero P*. Are We Ready for Bariatric Surgery in a Liver Transplant Program? A Meta-Analysis. Obesity Surgery, 2021, 31, 1214-1222, PMID: 33225408, FI: 3.479

Febrero B, Almela-Baeza J, Ros I, ..., Ramirez P. The impact of information and communications technology and broadcasting on YouTube for improving attitude toward organ donation in secondary education with the creation of short films. Patient Education and Counseling, 2021, 104, 2317-2326, PMID: 33658142, FI: 3.467

Serrano AB, DIaz-Cambronero O, Melchor-RipollEs J et al. COLABORADORES: Abad-Gurumeta A, Abad-Motos A, Aisa-Gasca M, ..., Mengual-Ballester M et al. Neuromuscular blockade management and postoperative outcomes in enhanced recovery colorectal surgery: secondary analysis of POWER trial. Minerva Anestesiologica, 2021, 87, 13-25, PMID: 33538417, FI: 3.396

Lopez-Jornet P*, Aznar C, Ceron J et al. Salivary biomarkers in breast cancer: a cross-sectional study. Supportive Care in Cancer, 2021, 29, 889-896, PMID: 32529492, FI: 3.359

de Groot N, Farinas F, Cabrera-Gomez CG, ..., Ramis G*. Weaning causes a prolonged but transient change in immune gene expression in the intestine of piglets. Journal of Animal Science, 2021, 99, PMID: 33640983, FI: 3.338

Vallecillos A, Maria-Dolores E, Villa J, ..., Ramis G et al. Phenotypic and Genetic Components for Growth, Morphology, and Flesh-Quality Traits of Meagre (Argyrosomus regius) Reared in Tank and Sea Cage. Animals, 2021, 11, PMID: 34828015, FI: 3.231

Vallecillos A, Marin M, Bortoletti M, ..., Ramis G et al. Genetic Analysis of the Fatty Acid Profile in Gilthead Seabream (Sparus aurata L.). Animals, 2021, 11, PMID: 34679910, FI: 3.231

Garcia de Los Rios Y Loshuertos A, Soler Laguia M, Arencibia Espinosa A ..., Garcia-Carrillo N et al. Comparative Anatomy of the Nasal Cavity in the Common Dolphin Delphinus delphis L., Striped Dolphin Stenella coeruleoalba M. and Pilot Whale Globicephala melas T.: A Developmental Study. Animals, 2021, 11, PMID: 33567775, FI: 3.231

Bano-Otalora B*, Rol MA*, Madrid JA*. Behavioral and Thermoregulatory Responses to Changes in Ambient Temperature and Wheel Running Availability in Octodon degus. Frontiers in Integrative Neuroscience, 2021, 15, 684988, PMID: 34276317, FI: 3.213

Pardo-Zamora G, Martinez Y, Moreno JA, Ortiz-Ruiz AJ. Treatment of Stage 2 Medication-Induced Osteonecrosis of the Jaw: A Case Series. International Journal of Environmental Research and Public Health, 2021, 18, PMID: 33498884, FI: 2.945

Vicente Ascension*, Rodriguez-Lozano Francisco Javier, Martinez-Beneyto Yolanda, ..., Ortiz-Ruiz Antonio J.*. Biophysical and Fluoride Release Properties of a Resin Modified Glass Ionomer Cement Enriched with Bioactive Glasses Symmetry-Basel, 2021, 13, PMID: null, FI: 2.94

Valverde I, Espin S*, Gomez-Ramirez P, ..., Garcia-Fernandez AJ*. Wildlife poisoning: a novel scoring system and review of analytical methods for anticoagulant rodenticide determination. Ecotoxicology, 2021, 30, 767-782, PMID: 33864551, FI: 2.935

Espin S, Sanchez-Virosta P. A review of metal-induced effects on vitamins A, E and D3 in birds. Ecotoxicology, 2021, 30, 1-16, PMID: 33151447, FI: 2.935

Torres-Costa M, Flores B, Torregrosa N, ..., Rodriguez JM. Malignant prediction in paragangliomas: analysis for clinical risk factors. Langenbecks Archives of Surgery, 2021, 406, 2441-2448, PMID: 34101001, FI: 2.895

Gomez-Ruiz AJ, Gonzalez-Gil A, Gil J, ..., Cascales-Campos PA*. Acute renal disease in patients with ovarian peritoneal carcinomatosis treated with cytoreduction and HIPEC: the influence of surgery and the cytostatic agent used. Langenbecks Archives of Surgery, 2021, 406, 2449-2456, PMID: 34283300, FI: 2.895

Lopez-Lopez V, Brusadin R, Lopez-Conesa A, ..., Robles-Campos R. Preoperative transarterial chemoembolization for laparoscopic liver resection in Child A cirrhotic patients with hepatocellular carcinoma. Langenbecks Archives of Surgery, 2021, 406, 763-771, PMID: 33411038, FI: 2.895

Castellino Giuseppa, Mesa Francisco, Cappello Francesco, ..., Cabello Inmaculada et al. Effects of Essential Oils and Selected Compounds from Lamiaceae Family as Adjutants on the Treatment of Subjects with Periodontitis and Cardiovascular Risk Applied Sciences-Basel, 2021, 11, PMID: null, FI: 2.838

Martinez-Lopez E*, Herrero D, Lopez-Berenguer G et al. Total Arsenic Concentrations in Sea Turtle Tissues from the Mediterranean Coast of Spain. Bulletin of Environmental Contamination and Toxicology, 2021, 107, 820-826, PMID: 33978774, FI: 2.807

Candel-PErez C, Santaella-Pascual J, Ros-Berruezo G, MartInez-GraciA C. Occurrence of Clostridioides (Clostridium) difficile in Poultry Giblets at Slaughter and in Retail Pork and Poultry Meat in Southeastern Spain. Journal of Food Protection, 2021, 84, 310-314, PMID: 33513258, FI: 2.745

Baeza-Murcia M, Valero-Navarro G, Pellicer-Franco E, ..., Aguayo-Albasini JL. Early diagnosis of anastomotic leakage in colorectal surgery: prospective observational study of the utility of inflammatory markers and determination of pathological levels. Updates in Surgery, 2021, 73, 2103-2111, PMID: 34018141, FI: 2.692

Martinez-Beneyto Y*, Ausina-Marquez V, Exposito-Delgado AJ et al. Spanish Dentists' Awareness, Knowledge, and Practice Regarding COVID-19: A Multiple Regression Analysis. International Dental Journal, 2021, 71, 530-539, PMID: 33795144, FI: 2.607

Ceballos-Francisco D, Garcia-Carrillo N, Cuesta A, Esteban-Abad M . Ultrasonography study of the skin wound healing process in gilthead seabream (Sparus aurata). Journal of Fish Diseases, 2021, 44, 1091-1100, PMID: 33760262, FI: 2.58

Flores-Funes D, Aguilar-Jimenez J, Martinez-Galvez M, ..., Ayala-De La Pena F*, ..., Aguayo-Albasini JL. Development of a predictive score of axillary lymph node dissection based on targeted axillary dissection in patients with breast cancer diagnosis, affected lymph nodes, and neoadjuvant treatment. Surgical Oncology-Oxford, 2021, 38, 101629, PMID: 34171793, FI: 2.388

Flores-Funes D, Aguilar-Jimenez J, Martinez-Galvez M, ..., Ayala-De La Pena F* et al. Feasibility and validation of the targeted axillary dissection technique in the axillary staging of breast cancer after neoadjuvant therapy: Definitive results. Surgical Oncology-Oxford, 2021, 38, 101636, PMID: 34303211, FI: 2.388

Fernandez-Ruiz VE, Sole-Agusti M, Armero-Barranco D et al. Weight Loss and Improvement of Metabolic Alterations in Overweight and Obese Children Through the I(2)AO(2) Family Program: A Randomized Controlled Clinical Trial. Biological Research for Nursing, 2021, 23, 488-503, PMID: 33517762, FI: 2.318

Moreno Rodriguez JA*, Pecci-Lloret M, Ortiz Ruiz E, Ortiz Ruiz AJ. Preliminary Results of a Minimally Invasive Microsurgical Approach to Sinus Floor Elevation and Bone Reconstruction Using a Palatal Septum Window. International Journal of Periodontics & Restorative Dentistry, 2021, 41, e255-e263, PMID: 34818393, FI: 2.227

Gomez-Roig MD, Pascal R, Cahuana MJ, ..., Larque E et al. Environmental Exposure during Pregnancy: Influence on Prenatal Development and Early Life: A Comprehensive Review. Fetal Diagnosis and Therapy, 2021, 48, 245-257, PMID: 33735860, FI: 2.208

Almansa-Saura S, Lopez-Lopez V, Eshmuminov D, ..., Robles-Campos R. Prophylactic Use of Negative Pressure Therapy in General Abdominal Surgery: A Systematic Review and Meta-Analysis. Surgical Infections, 2021, 22, 854-863, PMID: 33844934, FI: 1.853

Gomez-Peralta F, Menendez E, Conde S et al. COLABORADORES. ...,Hernandez-Martinez AM,... Clinical characteristics and management of type 1 diabetes in Spain. The SED1 study. Endocrinologia Diabetes y Nutricion, 2021, 68, 642-653, PMID: 34906345, FI: 1.833

Rezaei F, Imani MM, Lopez-Jornet P* et al. Estimation of serum and salivary matrix metalloproteinase levels in oral squamous cell carcinoma patients: a systematic review and meta-analysis. Postepy Dermatologii i Alergologii, 2021, 38, 106-114, PMID: 34408576, FI: 1.664

Lopez-Lopez V, Gomez Ruiz A, Pelegrin P, ..., Robles Campos R. Impact of Immune Response in Short-term and Long-term Outcomes After Minimally Invasive Surgery for Colorectal Liver Metastases: Results From a Randomized Study. Surgical Laparoscopy Endoscopy & Percutaneous Techniques, 2021, 31, 690-696, PMID: 34292210, FI: 1.455

Perez-Silva A*, Cury JA, Martinez-Beneyto Y, ..., Ortiz-Ruiz AJ*. [Total and soluble fluoride concentration in children s toothpastes in Spain.] Revista Espanola de Salud Publica, 2021, 95, PMID: 33828069, FI: 1.333

Perez Sayans M, Rivas Mundina B, Chamorro Petronacci CM, ..., Lopez Jornet P*. Effect of mesoporous silica and its combination with hydroxyapatite on the regeneration of rabbit's bone defects: A pilot study. Bio-Medical Materials and Engineering, 2021, 32, 281-294, PMID: 33780356, FI: 1.234

Wanden-Berghe C, Virgili Casas N, Cuerda Compes C, ..., Garcia-Zafra MV et al. [Home and Ambulatory Artificial Nutrition (NADYA) Group report: home parenteral nutrition in Spain, 2019]. Nutricion Hospitalaria, 2021, 38, 1304-1309, PMID: 34670394, FI: 1.169

Tomas Luiz A, Martin Pozuelo G, Gonzalez Navarro I, ..., Periago MJ*. [Influence of dietary carotenoids on biomarkers of cardiometabolic risk in peri- and post-menopausal women]. Nutricion Hospitalaria, 2021, 38, 993-1001, PMID: 34281348, FI: 1.169

Lopez-Lopez V, Martinez-Caceres C, Ferreras D, ..., Ramirez P. Biomarkers of Early Liver Graft Damage in Circulatory Death and Brain Death Donors: A Propensity Score Matching Analysis. Transplantation Proceedings, 2021, 53, 2659-2662, PMID: 34602295, FI: 1.014

Perez-Silva A*, Abad-Madrid M, Serna-Munoz C, ..., Cabello I*, Ortiz-Ruiz AJ. [Design and evaluation of a booklet for the Oral Health Program in children from birth]. Anales del Sistema Sanitario de Navarra, 2021, 44, 253-260, PMID: 34142988, FI: 0.892

AYUDAS CONCEDIDAS EN 2021

TOTAL DE AYUDAS CONCEDIDAS

Nº Ayudas

3.04M €

Financiación

TOTAL DE AYUDAS RECURSOS HUMANOS CONCEDIDAS

Nº Ayudas

1.05M €

Financiación

TOTAL DE AYUDAS PROYECTOS I+D+i CONCEDIDAS

Nº Ayudas Europeas

0.5M €

Financiación Europea

Nº Ayudas Nacionales

0.92M €

Financiación Nacional

Nº Ayudas Regionales

0.03M €

Financiación Regional

TOTAL DE REDES CONCEDIDAS

Nº Ayudas

0.12M €

Financiación

OTRAS AYUDAS COMPETITIVAS CONCEDIDAS (MOVILIDAD, ORGANIZACIÓN DE EVENTOS CIENTÍFICOS, ...)

Nº Ayudas

0.0K €

Financiación

PROYECTOS DE I+D+i Y AYUDAS DE RRHH ACTIVAS EN 2021

TOTAL AYUDAS

RECURSOS HUMANOS

REDES

PROYECTOS INTERNACIONALES

PROYECTOS NACIONALES

PROYECTOS REGIONALES

INICIADA EN 2021

Nº Estudios

Nº Ensayos Clínicos

Nº Producto Sanitario

Nº Estudios Post-Autorización

Nº Otros Estudios

ACTIVOS EN 2021

Nº Estudios

Nº Ensayos Clínicos

Nº Producto Sanitario

Nº Estudios Post-Autorización

Nº Otros Estudios

FACTURACIÓN EN 2021

0.01M €

Facturado

Nº Tesis (2 con mención internacional)